Prof., RNDr. Pavol Miškovský, PhD., DrSc.

Education:

1978 M.Sc. in Physics, Charles University, Prague, Czech Republic
1979 Rerum Naturalium Doctor in Physics, Charles University, Prague, Czech Republic
1986 Ph.D. in Biophysics, Charles University, Prague, Czech Republic
1993 Associate Professor (habilitation), Comenius University, Bratislava, Slovakia
2000 Doctor Scientarium (D.Sc.) in Biophysics, Comenius University, Bratislava, Slovakia
2001 Full Professor in Physics, P. J. Safarik University, Kosice, Slovakia

Languages

fluent in English, French, Russian, Czech and Slovak

Positions:

•Head of the Center of Interdisciplinary Biosciences, P. J. Safarik University, Kosice, Slovakia
•Full Professor and guarantee of undergraduate and doctoral study in biophysics, P.J. Safarik University, Kosice, Slovakia
•CEO SAFTRA Photonics LtD

Postdoctoral research training:

•1987–1988 Institute Curie, Lab. de Physicochimie Biomol. et Cellulaire, Paris, France (6 months)
•1992 Institute Curie, Lab. de Physicochimie Biomol. et Cellulaire, Paris, France (11 months)
•1993 Dipartimento di Biochimica, Universitá di Bologna, Italy, (2 months)

Invited professor positions:

• 1993–1996, Université P. et M. Curie, Paris, France, (4 month/year)
• 1998, Université P. et M. Curie, Paris, France, (1 month)
• 2003, Université d’Orleans, Orleans, France (1 month)
• 2004, Instituto de Estructura de la Materia, CSIC, Madrid (3 months sabbatical stay)
• 2005–2007, Université d’Orleans, Orleans, France (2 months/year)
• 2006 Iowa State University, Ames, USA (3 months) – Fulbright fellowship
• 2011 Université P. et M. Curie, Paris, France, (1 month)
NATO “Expert visit” grants
• Instituto de Estructura de la Materia, Madrid, Spain, 1997, 2003 (three weeks/year)
• Université P. et M. Curie, Paris, France, 2000 (three weeks)

Honor and awards

•Award of the Czechoslovak government for results in applied science 1989
•Awards from international fairs: Gold medal for „Flow Injection Analyzer PIA-O1“ from international fair „Zeme Zivitelka“ – Ceské Budejovice, Czech Republic, 1989
•Award of the President of the Faculty of Sciences, Safarik Univ. (results in science), 1997, 2010
•invitations for prestigious publications peer reviewed journals (see publications of P.M.)
•qualification for “Full Professor” positions in France (2002–2005) – branches: 1) 28 – condense matter and materials, and 2) 30 – diluted matter and optics
•member of the Int. Scientific and Advisory Committee of the Seventh and the Eighth Int. Conf. of Solar En. Storage and Appl. Photochrm. (2003 & 2005 Luxor, Egypt)

Research interest:

P.M. is working in interdisciplinary bio-research, recently mainly oriented to (see research grants):

9. photo-physics, photo-chemistry and photo-biology of antitumor photoactive agents: mechanism of their antitumor action (from molecular and cellular levels up to application in photodynamic therapy of cancer)

ii) structure and conformation of biological macromolecules and their interactions with drugs (application of sophisticated biophotonics methods)

Selected scientific projects (P.M. principal investigator):

I. Science grant agency of the Ministry of education of the SR and of the Slovak Academy of Sciences (VEGA)

1.VEGA 1/3258/96 (1996 – 1998) Antiviral activity of aromatic polycyclic dions: Mechanism of interaction on cellular and molecular levels: 10 000 €, principal investigator
2.VEGA 1/6027/99 (1999–2001) Antiviral and Antitumor Activity of Hypericin and Hypocrellin: Mechanism of inter. at cell. and mol. levels and its correlation with intramol. proton transfer: 12 000 €, principal investigator
3.VEGA 1/9040/02 (2002 – 2004) Antiviral and Antitumor Activity of nat. photoactive mol. Hypericin and Hypocrellin: Int. with boil. Macromol. and mechanism of action at cell. and mol. levels: 11 000 €, principal investigator
4.VEGA 1/2278/05 (2005 – 2007) Interaction of natural photosensitizers hypericin and canphostin C with regulatory and transport proteins: 15 000 €, principal investigator

II. Science and Technology Assistance Agency (APVV)

5.APVT-20–0222–02 (2002–2004) New Physical and Chemical Approaches to Photodynamic Therapy of Cancer: 98000 €, principal investigator
6.APVV-20–036104 (2005–2007) Photodynamic Therapy of Cancer : Mechanism of action of new antrachinones molecules: 135 700 €, principal investigator
7.APVV-0449–07 (2008–20010) Targeted photodynamic therapy> 280 000 €, principal investigator
8.APVV- LPP 0337–06 (2006–2010) Photodynamic therapy of cancer in the light of new molecular knowledge: 139.000 €, principal investigator
9.APVV- LPP 0072–07(2008–2012) Increasing of the efficiency of cancer therapy by targeted transport of photoactive drugs: 158.000 €, principal investigator
10.APVV- LPP 0290–09 (2009–2013) Development of optical nanosensors for multicomponent analysis of trace quantities of drugs and environment pollutants: 83.000 €, principal investigator

III. Grants of the European Union:

11.TEMPUS JEP 2327, (1991–1994) Centers for Master’s and Doctoral Studies, and Continuous Education in Biophysics and Chemical Physics: ~150 000 USD, for the Department, co-PI, responsibility for the Slovak partner)

12.Marie Curie reintegration grant No PIRG06-GA-2009–256580 (2010–1013): “MonInterFluoProt” 75.000 €, principal investigator

13.FP7 (2013–2016) “Fostering excellence in multiscale cell imaging” CELIM 316312, 2.600.000 €, principal investigator

14. H2020 (2016) “Disruptive portable device for pre-screening of Persistent Organic Pollutants –POPs- in food products and water (NanoScreen 66266)” SME instrument NMP 25 – 2014/2015

IV. Grant agencies of the USA:

14. NSF-CHE 1396 (1998–2001), Proton Transfer in Biomolecules: Interaction of Hypericin with Model Cellular Components: 40.000 USD, for the Department, coPI

V. NATO grants:

15. CBP.EAP.CLG 981432 (2005–2007), Detection of trace quantities of molecules by chemical sensors based on metallic nano-particle surfaces: 12.500 € principal investigator

VI. Internacional bilateral projects:

16.France-Slovakia, (1998–2001) Development and Characterization of a New Class of Antiviral and Antitumor Photoactive Agents: 9.000 € for the Slovak partner coPI

17. France-Slovakia, (project Stefanik) (2006–2007) Intracellular mechanism of anticancer activity of photoactive molecules: 4.000 €, for the Slovak partner, coPI

18.Czech Republic – Slovakia, 343/300, (2000–2002) Study of anticancer and antiviral activity of polycycling dions: 3.000 € for the Slovak partner, coPI

19. Czech Republic – Slovakia, 021/042 (2003–2005), Study of anticancer and antviral activity of new photoactive agents hypericin and hypocrellinA: 5.000 € for the Slovak partner, coPI

VII. Structural Regional Grants of the European Union:

20. SEPO (Network of excellence in oncology) (2009–2011): 120.000 € for the Department, coPI
21. CEVA (Center of excellence for respiration diseases) (2010–2012): 750.000 € for the Department, coPI
22. NanoBioSens (Development of optical nano-sensors for multicomponent analysis of trace quantities of pollutants and drugs) (2011–2013): 800.000 € for the Department, principal investigator
23. DOKTORAND (Modernization of doctoral study in natural sciences) (2010–2013): 250.000 € for the Department, principal investigator

Experience with EU FP6 and FP7 projects:

yes (FP6 (coPI), FP7(coPI) and H2020 (PI), EU expert (PF5–7, H2020))

Management activities

P.M. is
•guarantee of undergraduate and doctoral study in Biophysics at P. J. Safarik Univ., Kosice, Slovakia
•president of the habilitation (nomination of docents) and inauguration (nomination of professors) commission in biophysics at P.J. Safarik University, Kosice, Slovakia
•president of the National Scientific Committee for D.Sc. ( Doctor Scientarium ) degree in biophysics
•member of the Science Committee of the Faculty of Sciences, Safarik Univ., Kosice, Slovakia
•member of the Science Committee of the International laser Center, Bratislava
•member of the Executive Committee of the European Biophysical Societies' Association (EBSA) 2013 – 2015
•member of the Executive Committee of the Slovak Biophysical Society (SKBS) 2009 –

P.M.was
•member of the Comm. for doctoral thesis defense, P. et M. Curie Univ., Paris, France, 1995, 1998, 2000
•member of the Habilitation Committee, Orleans Univ., Orleans, France (2004)
•president of the organizing committee of the symposium of the Slovak biophysical Society 2004, 2006
•member of the Committee for Doctoral Study in Physics of Molecular and Biological Structures, Charles University, Prague, Czech Republic, 1992–2000
•member of the National Committee for doctoral study in Biophysics, Faculty of Mathematics and Physics, Comenius University, Bratislava, 1991 – 1996, and vice-president 1997-
•member of the Steering Committee and national coordinator of the EU JEP 2327 TEMPUS project (1991–94)
•responsible for the agreement between the Safarik Univ. and the Univ. P. et M. Curie, Paris, France (from 1994)
•member of the group of experts of the Slovak Accreditation Commission (Physics) (1998–2002)
•member of the Science Committee of the Fac. of Medicine, P.J.Safarik Univ., Kosice, Slovak Republic (1998–2004)
•chairman of the international Workshop on Biophotonics and Molecular Simulations, Bratislava 2006
•president of the Slovak Biophysical Society, 2001–2009

International collaboration of P.M.:

University of P. et M. Curie, Paris, France, Dep. of Chemistry, Iowa State University, USA, Instituto de Estructura de la Materia, Madrid, Spain, Institute of Physics, Charles University, Prague, Czech Republic, Swiss Federal Institute of Technology, Switzerland , Synchrotron SOLEIL, Gif-sur Yvette, France, Centre de Biophysique Moléculaire, CNRS, Orleans, France,

Invited congress lectures:

41 lectures (international congresses) including 3 plenary lectures

Other invited lectures:

46 invited lectures at Universities and Research canters, in 6 countries (USA, France, Spain, Italy, Czech Republic and India)

Graduated PhD students:

•Alena Ansary (thesis defense: Université P. et M. Curie, Paris 1995)
•Jozef Ulicny (thesis defense: University of P. J. Safarik, Kosice 1996)
•Branislav Brutovsky (thesis defense : University of P. J. Safarik, Kosice 1998)
•Daniel Jancura (thesis defense: University of Comenius Bratislava 1999)
•Gabriela Fabriciova (thesis defense University of Comenius, Bratislava 1999)
•Eva Kocisová (thesis defense: Université P. et M. Curie, Paríž 1995) – co-tutoring doctoral study, with Paris VI University, France
•Jana Stanicova (thesis defense: University of Comenius, Bratislava 2001)
•Jozef Hitz (thesis defense: University of Comenius, Bratislava 2005)
•Silvia Kocanova (thesis defense : University of P. J. Safarik, Kosice 2005)
•Slávka Kascakova, (thesis defense: University of P. J. Safarik, Kosice 2005) – co-tutoring doctoral study, with University of Orleans, France
•Peter Gbur , (thesis defense: University of P. J. Safarik, Kosice 2010)
•Gejza Lajos , (thesis defense: University of P. J. Safarik, Kosice 2010)
•Stefan Balint, ( thesis defense: University of P. J. Safarik, Kosice 2010)
•Veronika Huntosova, (thesis defense: University of P. J. Safarik, Kosice 2010) – co-tutoring doctoral study, with Paris VI University
•Luboslava Buriankova, (thesis defense: University of P. J. Safarik, Košice 2010)
•Lenka Bryndzova, (thesis defense: University of P. J. Safarik, Košice 2012)
•Dana Petrovajova, (thesis defense: University of P. J. Safarik, Košice 2013)
•Diana Buzova, (thesis defense: University of P. J. Safarik, Košice 2011)

Publications:

124 publications in international peer-reviewed journals (see WOS database), cited more than 1000 times, H index 22

Kosice, October, 2016

• FTP
• Laboratórium
• Nástenka